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Therapeutic Class


MeloninTM tablet is a preparation of Melatonin. Melatonin is a hormone secreted by the pineal gland, involved in the synchronization of circadian rhythms to the diurnal light-dark cycle. The pharmacological mechanism of action in melatonin is believed to be based on its interaction with MT1, MT2 and MT3 receptors, as these receptors (particularly MT1 and MT2) are involved in the regulation of sleep and circadian rhythms in general. Melatonin helps to control the timing and release of female reproductive hormones. In addition to its hormonal actions, Melatonin has a strong antioxidant effects. It helps to strength the immune system.

• Monotherapy for the short-term treatment of primary insomnia characterized by poor quality of sleep in patients who are aged 55 or over
• Disrupted circadian rhythms (such as those suffering from jet lag or poor vision or those who work the night shift)
• Regulating sleep patterns in peri- or postmenopausal women
• Sleeping difficulties associated with autism spectrum disorder (ASD)

Insomnia: 3-6 mg one hour before bedtime

Jet lag: The standard dose is 3 mg daily for a maximum of 5 days. The dose may be increased to 6 mg if the standard dose does not adequately alleviate symptoms. The dose that adequately alleviates symptoms should be taken for the shortest period. The first dose should be taken on arrival at destination at the habitual bed-time.

Due to the potential for incorrectly timed intake of melatonin to have no effect, or an adverse effect, on re-synchronization following jet-lag, Melatonin 3 mg tablets should not be taken before 20:00 hour or after 04:00 hour at destination.

For children with Autism Spectrum Disorder (ASD): The usual starting dose is 3 mg Melatonin taken 30 minutes to one hour before bedtime.

MeloninTM Tablet: Box containing 3 strips of 10 tablets each. Each tablet contains Melatonin USP 3 mg.

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